It has been shown that a single dose of the Pfizer/BioNTech vaccine can improve the protection against the variant in people who have previously had Sars-Cov-2 infection. In contrast, among uninfected people, the immune response given in the first dose is not sufficient to rule out the risk of Covid-19.
A single dose of Covid vaccine can enhance protection against variants, but it is only suitable for people who have previously been infected with Sars-Cov-2. This is confirmed by the results of a new study conducted by Imperial College London, which aims to examine the immune response caused by the first dose of serum administered at the mRna. Pfizer/BioNTech It was chosen as an immunization campaign by health workers in the UK Postponed to 12 weeks Compared with the 3 doses indicated after the clinical trial, the booster dose.
Therefore, the British authorities decided to extend the time to ensure that more people are provided with at least one dose of the drug, so a 9-week time frame was discovered during this period, “People who have Previous mild or symptomatic SARS-Cov-2 infection, Showing significantly improved protection against English and South African variants“Indicate the scholars in the notes. Analysis, detailed in scienceHowever, highlighting “In people who have not been infected with Sars-Cov-2 before, the immune response is weaker after the first administration, which makes these people Potential risk variants“.
Collectively, these conclusions emphasize the importance of the second dose in ensuring complete protection of the symptomatic form of Covid-19. “Our results indicate that people who received the first dose of the vaccine and have not previously been infected with Sars-CoV-2 are not fully protected and will not receive attention. -Said Rosemary Boyton, professor of immunology and respiratory medicine at Imperial College London and lead author of the study. On the other hand, natural infection alone may not provide sufficient immunity against variants.Boost with a single dose of vaccine Among people who have previously been infected“.