One year after discovering that cheap steroid drugs (such as dexamethasone) reduce the number of deaths caused by covid-19 by reducing the inflammatory response to the virus, scientists have discovered another life-saving treatment.
It is an infusion of monoclonal antibodies that neutralize the virus.
Many people will remember that U.S. President Donald Trump received various therapies such as monoclonal antibody-based therapies. He also treated his close partner, former New York mayor and lawyer Rudy Giuliani.
Although at risk due to age, both recovered relatively quickly. But to this day, it is not clear how all the treatments they receive will help them. Trump was very impressed with the monoclonal therapy, and he promised to make it available to all Americans. Since then, more than 250,000 such therapies have been distributed, but they have not been shown to be particularly effective in clinical trials.
Similar to Trump, a new study was conducted by taking the anti-inflammatory steroid drug dexamethasone, which alone can reduce the risk of death for the most severe covid-19 patients by about a third.
Sir Peter Hobby, one of the study leaders, explained that there is great uncertainty as to whether antibody therapy is the right approach, because some studies have not found significant benefits.
For example, the administration of convalescent plasma to those patients who survived covid-19 has not proven to be effective.
However, Regeneron’s new therapy uses large doses of two laboratory-made specific antibodies, which bind well to the SARS-CoV-2 virus.
Hobby said: “It is great to learn that even with advanced COVIDa-19, targeting the virus with antibodies can reduce the mortality of patients who fail to develop an immune response.”
The results of the new trial show that treatment can help any third person admitted to the hospital with severe covida-19 symptoms.
In about 100 patients receiving treatment, this treatment can save 6 lives.
The monoclonal antibodies developed by Regeneron work by binding to viruses and preventing them from entering and reproducing in cells.
According to the BBC, in a study involving nearly 10,000 hospitals in the UK, the therapy significantly reduced:
-Risk of death
-Hospitalization time is about four days