American scientists reported in the journal Nature on Monday that several months after recovering from the mild form of covida-19, when the level of antibodies in the blood drops, the immune cells in the bone marrow are still able to secrete new antibodies against the coronavirus. .
After infection, short-lived immune cells will quickly produce and secrete a series of protective antibodies.
As immune cells die, antibody levels will drop, but the collection of these immune cells (called long-lived plasma cells) retains a certain reserve even after infection.
Study co-author Ali Ellebedy of Washington University School of Medicine in St. Louis explained that most of them moved to the bone marrow.Louis
He said that seven months after the onset of the mild form of covida-19, 19 patients provided bone marrow samples to members of his scientific team.
It was found that fifteen of the plasma cells were long-lived and could secrete antibodies against the coronavirus.
Eleven months after the onset of symptoms, five of them underwent a second bone marrow biopsy, which showed that all patients still had long-lived plasma cells secreting anti-SARS-CoVa-2 antibodies.
Ellebedy pointed out that these “cells remain in the bone marrow and continue to secrete antibodies.” He explained that they have been acting this way since the end of the disease, and this situation is likely to continue indefinitely.
The author of the study said: “These cells will continue to survive and may produce antibodies for the rest of people’s lives, but it is not clear whether we will have the same results in patients who survive moderate to severe covida-19. “to sum up.