More than one million French children under 55 years of age under 55 years of age have to be injected with Pfizer or Moderna vaccine after a dose of AstraZeneca vaccine. The recommendations of France’s main health advisory committees are almost certainly taken over by the government.
The country recently decided to only vaccinate AstraZeneca for people over 55 years of age.Like many other countries, France may bandage Between the AstraZeneca vaccine and rare thrombosis.
In the Netherlands, the Health Commission recommends that those who have been injected with AstraZeneca for the first time can have a second injection as planned. There is no second case of serious side effects of AstraZeneca injection in the world. The very rare side effects reported occurred within two weeks after the first injection.
Combination vaccine research
Therefore, France has a different view on this. But, as suggested there, is the combination vaccine safe and effective? Anke Huckriede, a professor of vaccinology at the University of Groningen, said: “This is still under investigation.” “In six to eight weeks, we will show for the first time whether this combination of injections can resemble two vaccinations. The same vaccine is as effective in triggering an immune response.”
The research she mentioned was conducted in the UK by Oxford University and the pharmaceutical company Pfizer.Where it combines AstraZeneca and Pfizer vaccines after testing Among 820 people over 50 years old. Some get AstraZeneca first, then Pfizer, others do the opposite. Two different time intervals were used between the two injections: one group had a four-week interval between the two injections, and the other group had a twelve-week interval between the first injection and the second injection.
Huckriede said: “It seems reasonable that the combination of injections works well.” “But research must prove this.”
Dimitri Diavatopoulos, an immunologist at Radboud UMC, said that it is even possible that a combination of vaccines is more effective than two injections of the same vaccine. He said that AstraZeneca and Pfizer are different vaccines, “but they both target the spike protein of the virus.” “We know from research that combining different vaccine responses is actually beneficial.”
Diavatopoulos explained that AstraZeneca and Pfizer induce immunity in different ways. “If you do this in several ways, you will get a broader immune response. This is how it works in all completed animal studies, and it can also work in humans. It has not yet been used in mRNA vaccines. Extensive research has been conducted on the Internet because they have never been used in humans before.”
The first results of the UK study are expected to be released around early June, which will not only further illustrate the safety and effectiveness of the Astra-Zeneca/Pfizer combination, but also what impact it will have on new variants of the coronavirus.
By the way, a combination of different vaccines has been carried out in the vaccination program against Ebola, measles and other viruses.
After reports that may be related to thrombosis, people’s confidence in the AstraZeneca vaccine declined. In France, the initial willingness to vaccinate is low, polling Seeing that 71% of French people do not trust AstraZeneca.
This is in sharp contrast to the French confidence in Pfizer and Moderna vaccines, which have 70% and 65% confidence respectively. By the way, compared with December last year, the overall vaccination willingness of the French population has been greatly improved, from 42% at that time to 71% now.